Main Ingredients in Cialis
Cialis: Prehistory
When it comes to problems with men's health, most people think not about headaches, colds or depression, but about erectile dysfunction. It is quite natural, since this problem worries the male population of our planet much more than any other diseases, even much more dangerous. Nothing hurts a man's self-esteem more and casts him into greater uncertainty than problems on the sexual front. Not surprisingly, pharmacological companies and healthcare providers around the world have over the years tried to develop the most effective cure for male sexual impotence. Finally, their efforts were crowned with success: in the USA in the middle of 1990s a new medication (Cialis) against erectile dysfunction was developed. By that time Viagra was already invented and became famous all over the world, but the newly developed drug has surpassed it in many respects, although because of the fact that it was not the first effective means for potency, it did not rank first in popularity in the world. That great American drug Cialis which saved and continues to save men of all ages, nationalities and religions from problems in the sexual sphere is called Cialis. In the current article we will review its main ingredient and will find out how it affects reproductive system of a man’s organism and what are its properties.
What Is The Main Ingredient in Cialis?
The main ingredient in Cialis is the chemical substance named Tadalafil. In its pure form it is a crystalline solid substance, practically insoluble in water.
It belongs to the pharmacological group of potency regulators, namely, PDE-5 inhibitors Cialis. The pharmacological effect of Cialis Tadalafil – increase of potency, stimulation of occurrence of erection – is based on its ability to boost release of nitric oxide. The normal functioning of potency is due to the fact that sexual stimulation, caresses, the state of sexual arousal cause intense release of nitric oxide, leading to relaxation of the smooth muscles of the penis, its vessels, and to the activation of blood circulation in the genital area. The rush of blood to tissues of the penis stimulates the onset of an erection. It should be mentioned that Cialis not only improves erection, but also significantly prolongs the duration of every sexual act. This property of Cialis is often taken into consideration as a means of treatment of premature ejaculation.
Unlike many other medications used for the treatment of erectile dysfunction, Cialis Tadalafil maintains its effectiveness during more than a day, up to 36 hours, and in some cases even more, while the effect appears very soon – in about twenty minutes, maximum in an hour. Such a long period of action is unique on today’s market of potency drugs Cialis.
Is Cialis (Tadalafil) Addictive?
It is worth noting a very important thing: Cialis with its active substance Tadalafil has nothing in common with a narcotic drug, while sometimes uneducated people say the opposite, refusing to treat their sexual problems with the help of any medications. Tadalafil (Cialis) is not addictive even in the case of regular (or permanent) reception. Of course, a man can get used to perceive sex without anxiety only after taking the pill of Cialis, but it is rather an individual psychological reaction that quickly passes by itself. Still, if you can’t imagine the possibility of a full sexual life without taking the medicine (Cialis) and you don’t have any serious erection disorders, it is advised to consult with a psychologist about this problem or your healthcare provider .
Some men mention that after a long reception of the drug they need a larger dosage in order to feel the effect of Cialis (Tadalafil) and become frightened that they became drug addicts. This is not connected with any addiction on cialis; usually such a situation takes place if the condition of your reproductive system has worsened, for example, you’ve gained extra weight, or began to lead a sedentary lifestyle, that is, if in your life appeared factors that adversely affect your potency. In such cases, your body will need more Cialis Tadalafil to achieve a good erection. This is a signal, however, not to increase the dosage, but to reconsider your way of life and eliminate these negative factors. Usually if you take these measures, initial dosage of the main ingredient of Cialis will remain effective for you.
Contraindications to Tadalafil
Cialis is contraindicated in men having allergic reaction to Tadalafil, in case of simultaneous reception of drugs containing organic nitrates, and in case of medical restrictions imposed on sexual activity. The last situation is usually connected with serious heart diseases and vascular pathologies. Persons with renal and hepatic insufficiency should take the drug under the strict supervision of a physician and healthcare provider or pharmacist. It is not recommended to take Cialis if you have any degenerative diseases of the retina, anatomical deformities of the penis. You should be careful taking Cialis Tadalafil if you suffer from high blood pressure, arrhythmia, Peyronie's disease. You can clarify the contraindications to Cialis with your urologist or healthcare provider, if you don’t know what kind of concomitant diseases you suffer from. Cialis is approved for use in men over 18 years of age.
Side Effects of Cialis
The active ingredient of Cialis has become famous due to the fact that it provides considerably fewer side effects than any other drug used to date for the treatment of erectile dysfunction. However, it is not completely free of them. Side effect of Cialis (Tadalafil) can be divided into three groups: frequently, rarely and almost never occurring.
Frequent Cialis side effects are headache, stuffiness of the nose, reddening of the eyes. Dyspepsia, muscle pain in the back, cardiopalmus belong to much more seldom appearing unpleasant sensations. Very seldom a patient can experience nose bleed, nausea, impaired visual acuity and color perception. Such effects of Cialis occur in no more than one percent of men.
Complete list of Cialis side effects is usually presented in the instruction manual of the drug and healthcare provider. Usually, unpleasant sensations are most pronounced at the first intake of the drug, and tend to decrease with time if you continue the treatment.
Cialis (Tadalafil) against Orchialgia
Cialis drugs used to treat Orchialgia. Orchialgia is a pathological condition of the male reproductive system in which a man experiences a chronic sensation of tension and/or pain in the testicle, epididymis or spermatic cord, provided there is no inflammatory disease or injury. Both one and both testicles can be affected. These symptoms are very detrimental to the psychological state of a man and greatly spoils the quality of life and health.
Quite often, the occurrence of pain is noted after complicated sexual postures, lifting large weights, long stay in the sitting position, for example, while driving a car or riding a bicycle, as well as during neurosis. In addition, pain may accompany chronic prostatitis.
A recent study, which was presented at the AUA conference in San Francisco, showed that Levofloxacin in combination with Tadalafil is the most effective treatment for nonspecific testicular pain. Although the latter is mainly known for the treatment of erectile dysfunction, its effectiveness for the treatment of orchialgia has been noted. The optimal combination is the use of these medicines (Cialis) with physiotherapy for health.
Tadalafil VS Sildenafil
The rivalry between Cialis and Viagra in the US market of drugs for the treatment of erectile dysfunction has already become a kind of tradition ED medicines market. Although Sildenafil, as the active ingredient of Viagra, unlike cialis has a certain circle of its adherents, Cialis has a number of indisputable advantages. Among them are significantly fewer and less pronounced side effects, better tolerability of Tadalafil by the male organism, as well as the ability to take Cialis in courses, and not just “on demand”. Cialis tablet is suitable for many men who don’t tolerate Viagra. In addition, Cialis (Tadalafil) is an effective remedy used for treatment of BPH (benign prostatic hyperplasia), unlike Sildenafil. In this case, it is advised to take this medicine in a dosage of 5 mg daily. It is used in combination with other medications against BHP as well as a separate treatment, mostly at initial stages of the disease. The therapeutic effect is achieved by stimulating the blood supply to the organs of the small pelvis, eliminating stagnation of blood in the prostate gland and reducing its size. Please note that taking Cialis tablet as a means to treat diseases of the prostate gland is possible only after consulting an urologist!
Since Cialis in a dosage of 5 mg can be taken every day, regardless of whether you have sex or not, this is a great option for the prevention of violations of potency. Cialis 5 mg pills can be taken even without the advice of a doctor if you notice that you have begun to face difficulties in bed.
As well as Sildenafil, Cialis (Tadalafil) should not be combined with medications containing nitrates, as it may cause a sudden severe drop of arterial pressure. In general, the list of contraindications is almost the same for both these drugs.
Tadalafil VS Avanafil
Avanafil, one of the newest drugs for combating erectile dysfunction, is a PDE-5 inhibitor, as well as the active substance of Cialis. It has been approved by FDA in 2012, and it is sold under two trade names – Stendra and Spedra. Both these medicines are branded ones, manufactured by American pharmaceutical company Vivus Inc. and Italian drug provider Menarini Group. At the US market Stendra by Vivus is available, while in Europe, Australia and New Zealand Avanafil is sold under the name Spedra.
This medication is an effective remedy against ED, which starts acting 30 minutes after intake. Its effectiveness can be compared with the one of Viagra, while being characterized by better tolerance by the patients. Avanafil unlike cialis is not suitable for daily intake, because the period of its action is only 5 or 6 hours, while Cialis remains in the organism up to 36 hours.
Comparing Avanafil and Cialis, it can be said that for patients with strongly pronounced impotence large dosages of Avanafil are preferable. As for milder erectile dysfunction, Cialis can be a better option. However, all these conclusions are relative, and in each case it is recommended to consult a doctor or your healthcare provider and undergo a medical examination for a more accurate choice of the drug Cialis. It is possible that the cause of problems with potency will not be directly related to the blood supply to the genital organs, and your doctor will prescribe you the treatment of inflammatory diseases of the urogenital system or some completely different ailment, such as osteochondrosis.
Tadalafil VS Vardenafil
Vardenafil is an active ingredient of Levitra pills, which belong to “Big Three” of medications against erectile dysfunction. Not being so commonly known as Viagra, Levitra still holds the third position among ED drugs on the US market. What are its advantages and disadvantages in comparison with Cialis?
There are no significant differences in the mechanism of action of these two drugs (Cialis and Tadalafil), because both of them belong to the class of PDE-5 inhibitors. However, as clinical studies and reports of the patients show, Levitra’s action unlike cialis is often stronger, i.e. it provides a more intense erection soon after the intake of a pill. The half-life of Levitra from the body is about 4.5 hours, so the medication lasts at least 8 hours, although the maximum activity phase occurs in the first 5 hours after taking the pill. Meanwhile, if a man wants to take medicine to increase his potency daily, Cialis is the better choice.
Compared with Cialis, Vardenafil has more pronounced side effects. In addition, quite often men note that Vardenafil contributes to a significant prolongation of sexual intercourse, which is not observed in the case of Cialis. For patients with premature ejaculation, this may be useful, but sometimes men complain that it is difficult for them to reach orgasm or its brightness is reduced. If there is no need to delay ejaculation, Cialis may be a more suitable option
Cialis has a smaller number of relative contraindications compared with Vardenafil and is great for men who are going to take medicine to restore potency for the first time due to its mild effect on the male organism.